| Gene Information | |
|---|---|
| Gene Name | PKCG |
| Organism | Homo sapiens (Human) |
| Gene Length | 697 |
| Protein Names | Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P05129 |
| Gene Card | PRKCG |
| Uniprot ID | P05129 |
| Pfam | PF00130; PF00168; PF00069; PF00433 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in Purkinje cells of the cerebellar cortex. {ECO:0000269|PubMed:12644968}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.036364(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2E73 (NMR - ) 2UZP (X-ray 2.00A ) |
| DBSNP | rs386134159 rs121918511 rs121918512 rs121918513 rs752933837 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:P63318}. Cytoplasm, perinuclear region {ECO:0000250}. Cell membrane {ECO:0000269|PubMed:29053796}; Peripheral membrane protein {ECO:0000250}. Synapse, synaptosome {ECO:0000250|UniProtKB:P63318}. Cell projection, dendrite {ECO:0000250|UniProtKB:P63319}. Note=Translocates to synaptic membranes on stimulation. {ECO:0000250|UniProtKB:P63318}. |
| Mouse PG classification | NA |
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