| Gene Information | |
|---|---|
| Gene Name | PKCA |
| Organism | Homo sapiens (Human) |
| Gene Length | 672 |
| Protein Names | Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P17252 |
| Gene Card | PRKCA |
| Uniprot ID | P17252 |
| Pfam | PF00130; PF00168; PF00069; PF00433 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.013953(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2ELI (NMR - ) 3IW4 (X-ray 2.80A ) 4DNL (X-ray 1.90A ) 4RA4 (X-ray 2.63A ) |
| DBSNP | rs34406842 rs6504459 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:23990668}. Cell membrane {ECO:0000269|PubMed:23990668}; Peripheral membrane protein {ECO:0000305|PubMed:23990668}. Mitochondrion membrane {ECO:0000269|PubMed:9738012}; Peripheral membrane protein {ECO:0000305|PubMed:9738012}. Nucleus {ECO:0000250|UniProtKB:P20444}. |
| Mouse PG classification | NA |
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