| Gene Information | |
|---|---|
| Gene Name | OAT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 542 |
| Protein Names | Organic anion transporter 3 (hOAT3) (Organic anion/dicarboxylate exchanger) (Solute carrier family 22 member 8) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8TCC7 |
| Gene Card | SLC22A8 |
| Uniprot ID | Q8TCC7 |
| Pfam | PF00083 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in kidney (PubMed:11306713, PubMed:11912245). Weaker expression in brain and skeletal muscle (PubMed:11306713). Expressed in adrenal glands (PubMed:15864504). {ECO:0000269|PubMed:11306713, ECO:0000269|PubMed:11912245, ECO:0000269|PubMed:15864504}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11568479 rs45566039 rs11568493 rs11568492 rs45438191 rs11568482 rs749944923 rs11568486 |
| Subcellular location [CC] | Basolateral cell membrane {ECO:0000269|PubMed:11306713}; Multi-pass membrane protein {ECO:0000305}. Note=Localizes on the brush border membrane of the choroid epithelial cells (By similarity). Localizes to the basolateral membrane of the proximal tubular cells (PubMed:11306713). Localizes on the abluminal and possibly, luminal membrane of the brain capillary endothelial cells (BCEC) (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:Q9R1U7, ECO:0000269|PubMed:11306713}. |
| Mouse PG classification | NA |
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