| Gene Information | |
|---|---|
| Gene Name | PHF7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 381 |
| Protein Names | PHD finger protein 7 (Testis development protein NYD-SP6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000010318 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BWX1 |
| Gene Card | PHF7 |
| Uniprot ID | Q9BWX1 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.913356832) |
| Ortholog in Animals | Alpaca_ PHF7 ( ortholog_one2one ) Dog_ PHF7 ( ortholog_one2one ) GuineaPig_ PHF7 ( ortholog_one2one ) Macaque_ PHF7 ( ortholog_one2one ) Mouse_ Phf7 ( ortholog_one2one ) Pig_ PHF7 ( ortholog_one2one ) Rat_ Phf7 ( ortholog_one2one ) Rabbit_ PHF7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | G2E3, PHF11, PHF6 |
| Tissue | testis |
| Tissue Specificity | Highly expressed in Sertoli cells, but not in germ cells in adult testis. Expression in embryonic testis is 30-times lower. Highly expressed in colon, spleen, white blood cells, pancreas, lung, liver, placenta and brain. Detected at lower levels in thymus, small intestine, ovary and kidney. {ECO:0000269|PubMed:11829468}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11829468}. |
| Mouse PG classification | NA |
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