Gene Information
Gene NamePITPNM1
OrganismHomo sapiens (Human)
Gene Length1244
Protein NamesMembrane-associated phosphatidylinositol transfer protein 1 (Drosophila retinal degeneration B homolog) (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2)
Target NameNA
Target TypeNA
Gene Age424 ( ENSG00000110697 )
Evolutionary StageEukaryota
AlphaFoldDBO00562
Gene CardPITPNM1
Uniprot IDO00562
PfamPF02862; PF02121
In ASDno
Allosteric Predictionno (-0.687692078)
Ortholog in AnimalsAlpaca_ PITPNM1 ( ortholog_one2one )
Dog_ CDK2AP2 ( ortholog_one2one )
GuineaPig_ PITPNM1 ( ortholog_one2one )
Macaque_ PITPNM1 ( ortholog_one2one )
Mouse_ Pitpnm1 ( ortholog_one2one )
Pig_ PITPNM1 ( ortholog_one2one )
Rat_ Pitpnm1 ( ortholog_one2one )
OhnologsPITPNM3
ParalogsPITPNM2, PITPNM3, PITPNC1, PITPNB, PITPNA
TissueNA
Tissue SpecificityUbiquitous. {ECO:0000269|PubMed:10022914}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm. Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:12225667};
Peripheral membrane protein. Endoplasmic reticulum membrane {ECO:0000269|PubMed:12225667};
Peripheral membrane protein. Lipid droplet {ECO:0000269|PubMed:12225667}. Cleavage furrow {ECO:0000269|PubMed:15125835}. Midbody {ECO:0000269|PubMed:15125835}. Note=Peripheral membrane protein associated with Golgi stacks in interphase cells. A minor proportion is associated with the endoplasmic reticulum. Associated with lipid droplets (PubMed:12225667). Dissociates from the Golgi early on in mitosis and localizes to the cleavage furrow and midbody during cytokinesis (PubMed:15125835). {ECO:0000269|PubMed:12225667, ECO:0000269|PubMed:15125835}.
Mouse PG classificationNA
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