| Gene Information | |
|---|---|
| Gene Name | PTPN20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 420 |
| Protein Names | Tyrosine-protein phosphatase non-receptor type 20 (hPTPN20) (EC 3.1.3.48) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000204179 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q4JDL3 |
| Gene Card | PTPN20 |
| Uniprot ID | Q4JDL3 |
| Pfam | PF00102 |
| In ASD | no |
| Allosteric Prediction | no (-0.876530476) |
| Ortholog in Animals | Alpaca_ PTPN20 ( ortholog_one2one ) Dog_ PTPN20 ( ortholog_one2one ) Macaque_ PTPN20 ( ortholog_one2one ) Mouse_ Ptpn20 ( ortholog_one2one ) Pig_ PTPN20 ( ortholog_one2one ) Rat_ Ptpn20 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PTPN12, PTPRC, PTPN6, PTPN18, PTPN7, PTPN1, PTPN13, PTPRF, PTPRK, PTPRB, PTPRA, PTPN22, PTPRG, PTPRR, PTPN5, PTPN23, PTPRZ1, PTPN9, PTPRE, PTPN4, PTPRT, PTPRS, PTPRD, PTPN2, PTPRO, PTPRJ, PTPRM, PTPN11, PTPRU, PTPN14, PTPN3, PTPRN, PTPRN2, PTPRH, PTPN21 |
| Tissue | NA |
| Tissue Specificity | Present in many cell lines (at protein level). Widely expressed. {ECO:0000269|PubMed:15790311}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15790311}. Cytoplasm {ECO:0000269|PubMed:15790311}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:15790311}. Note=Colocalizes with the microtubule-organizing center and intracellular membrane compartments. |
| Mouse PG classification | NA |
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