| Gene Information | |
|---|---|
| Gene Name | KDM2B |
| Organism | Homo sapiens (Human) |
| Gene Length | 1336 |
| Protein Names | Lysine-specific demethylase 2B (EC 1.14.11.27) (CXXC-type zinc finger protein 2) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (Protein JEMMA) (Protein-containing CXXC domain 2) ([Histone-H3]-lysine-36 demethylase 1B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000089094 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8NHM5 |
| Gene Card | KDM2B |
| Uniprot ID | Q8NHM5 |
| Pfam | PF00646; PF17811; PF16866; PF02008 |
| In ASD | no |
| Allosteric Prediction | yes (0.159909619) |
| Ortholog in Animals | Alpaca_ KDM2B ( ortholog_one2one ) Dog_ KDM2B ( ortholog_one2one ) GuineaPig_ KDM2B ( ortholog_one2one ) Macaque_ KDM2B ( ortholog_one2one ) Mouse_ Kdm2b ( ortholog_one2one ) Rat_ Kdm2b ( ortholog_one2one ) Rabbit_ KDM2B ( ortholog_one2one ) |
| Ohnologs | KDM2A |
| Paralogs | KDM2A, KDM7A, PHF8, PHF2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.063158(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4O64 (X-ray 2.13A ) 5JH5 (X-ray 2.55A ) 6BVA (X-ray 2.66A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:17994099}. Nucleus {ECO:0000269|PubMed:26237645}. Chromosome {ECO:0000269|PubMed:26237645}. |
| Mouse PG classification | NA |
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