Gene Information
Gene NameDRC3
OrganismHomo sapiens (Human)
Gene Length723
Protein NamesEpidermal growth factor receptor kinase substrate 8-like protein 1 (EPS8-like protein 1) (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-related protein 1)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000171962 )
Evolutionary StageEukaryota
AlphaFoldDBQ8TE68
Gene CardEPS8L1
Uniprot IDQ8TE68
PfamPF08416; PF18016; PF00018
In ASDno
Allosteric Predictionno (-1.935218007)
Ortholog in AnimalsAlpaca_ DRC3 ( ortholog_one2one )
Dog_ DRC3 ( ortholog_one2one )
GuineaPig_ DRC3 ( ortholog_one2one )
Macaque_ DRC3 ( ortholog_one2one )
Mouse_ Drc3 ( ortholog_one2one )
Pig_ DRC3 ( ortholog_one2one )
Rat_ Drc3 ( ortholog_one2one )
OhnologsNA
ParalogsLRRC43, DNAAF11, LRRCC1, LRRC9, LRRC46, DNAAF1, LRRC49, CEP97, LRRC23, PPP1R42, LRRC61, LRRIQ3, LRGUK
Tissueoviduct
Tissue SpecificityDetected in placenta. {ECO:0000269|PubMed:14565974}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2K2M  (NMR  2ROL  (NMR 
DBSNP rs12609976  rs1620074  rs1628576  rs1054940  rs60073068 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:14565974}.
Mouse PG classificationNA
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