| Gene Information | |
|---|---|
| Gene Name | DPY19L2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 758 |
| Protein Names | Probable C-mannosyltransferase DPY19L2 (EC 2.4.1.-) (Dpy-19-like protein 2) (Protein dpy-19 homolog 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000177990 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6NUT2 |
| Gene Card | DPY19L2 |
| Uniprot ID | Q6NUT2 |
| Pfam | PF10034 |
| In ASD | no |
| Allosteric Prediction | no (-1.319567106) |
| Ortholog in Animals | Alpaca_ DPY19L2 ( ortholog_one2many ) GuineaPig_ DPY19L2 ( ortholog_one2one ) Macaque_ DPY19L2 ( ortholog_one2one ) Mouse_ Dpy19l2 ( ortholog_one2one ) Pig_ DPY19L2 ( ortholog_one2one ) Rat_ Dpy19l2 ( ortholog_one2one ) Rabbit_ DPY19L2 ( ortholog_one2one ) |
| Ohnologs | DPY19L4 |
| Paralogs | DPY19L1, DPY19L3, DPY19L4 |
| Tissue | testis |
| Tissue Specificity | Widely expressed with high expression in testis. Not detectable in ejaculated sperm (at protein level). {ECO:0000269|PubMed:16526957, ECO:0000269|PubMed:21397064}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10878075 rs10878074 rs10878073 rs12314553 |
| Subcellular location [CC] | Nucleus inner membrane {ECO:0000250|UniProtKB:P0CW70}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with DPY19L2 at the inner nuclear membrane. {ECO:0000250|UniProtKB:P0CW70}. |
| Mouse PG classification | NA |
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