| Gene Information | |
|---|---|
| Gene Name | EXTR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 919 |
| Protein Names | Exostosin-like 3 (EC 2.4.1.223) (EXT-related protein 1) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Hereditary multiple exostoses gene isolog) (Multiple exostosis-like protein 3) (Putative tumor suppressor protein EXTL3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O43909 |
| Gene Card | EXTL3 |
| Uniprot ID | O43909 |
| Pfam | PF03016; PF09258 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Expressed in keratinocytes. {ECO:0000269|PubMed:22727489}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7AU2 (EM 2.43A ) 7AUA (EM 2.93A ) |
| DBSNP | rs747676107 rs116659770 rs554294508 rs1332006145 rs35781576 rs770842408 rs2269452 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10639137}; Single-pass type II membrane protein {ECO:0000269|PubMed:10639137}. Golgi apparatus {ECO:0000269|PubMed:28132690}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |