| Gene Information | |
|---|---|
| Gene Name | FAM50A |
| Organism | Homo sapiens (Human) |
| Gene Length | 339 |
| Protein Names | Protein FAM50A (Protein HXC-26) (Protein XAP-5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000071859 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q14320 |
| Gene Card | FAM50A |
| Uniprot ID | Q14320 |
| Pfam | PF04921 |
| In ASD | no |
| Allosteric Prediction | no (-0.857107629) |
| Ortholog in Animals | Alpaca_ FAM50A ( ortholog_one2one ) Dog_ FAM50A ( ortholog_one2one ) GuineaPig_ FAM50A ( ortholog_one2one ) Macaque_ FAM50A ( ortholog_one2one ) Mouse_ Fam50a ( ortholog_one2one ) Pig_ FAM50A ( ortholog_one2one ) Rat_ Fam50a ( ortholog_one2one ) Rabbit_ FAM50A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FAM50B |
| Tissue | NA |
| Tissue Specificity | Widely expressed in fetal and adult tissues. Mostly abundant in fetal brain, liver and kidney; in the adult, high levels were also observed in heart, skeletal muscle, spleen, thymus, prostate and small intestine. Expressed in fetal cerebellum and hypothalamus. Low expression is observed in fetal temporal lobe (PubMed:32703943). {ECO:0000269|PubMed:32703943, ECO:0000269|PubMed:9339379}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs149558328 rs782017549 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:32703943}. |
| Mouse PG classification | NA |
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