| Gene Information | |
|---|---|
| Gene Name | MAGED1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 778 |
| Protein Names | Melanoma-associated antigen D1 (MAGE tumor antigen CCF) (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000179222 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9Y5V3 |
| Gene Card | MAGED1 |
| Uniprot ID | Q9Y5V3 |
| Pfam | PF01454 |
| In ASD | no |
| Allosteric Prediction | no (-0.961727736) |
| Ortholog in Animals | Alpaca_ MAGED1 ( ortholog_one2one ) Dog_ MAGED1 ( ortholog_one2one ) Macaque_ MAGED1 ( ortholog_one2one ) Mouse_ Maged1 ( ortholog_one2one ) Pig_ MAGED1 ( ortholog_one2one ) Rat_ Maged1 ( ortholog_one2one ) Rabbit_ MAGED1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MAGED4, MAGED4B, MAGEB17, MAGEB1, MAGEA3, MAGEA6, MAGEL2, MAGEA2, MAGEA2B, MAGEA12, NDN, MAGEB6, MAGEB6B, MAGEB2, MAGEH1, MAGEA8, MAGEE2, MAGEA11, MAGEB5, MAGEB10, MAGEA10, MAGEA4, TRO, MAGEB4, MAGEC3, MAGEE1, MAGEA9, MAGEA9B, MAGEB3, MAGEC1, MAGEC2, NSMCE3, MAGEA1, MAGEB18, MAGEB16, MAGEF1, MAGED2 |
| Tissue | NA |
| Tissue Specificity | Expressed in bone marrow stromal cells from both multiple myeloma patients and healthy donors. Seems to be ubiquitously expressed. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.002240(Rat);0.025000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12689461 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Note=Expression shifts from the cytoplasm to the plasma membrane upon stimulation with NGF. {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |