| Gene Information | |
|---|---|
| Gene Name | PIF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 641 |
| Protein Names | ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) (PIF1/RRM3 DNA helicase-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000140451 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9H611 |
| Gene Card | PIF1 |
| Uniprot ID | Q9H611 |
| Pfam | PF05970 |
| In ASD | no |
| Allosteric Prediction | no (-0.377341248) |
| Ortholog in Animals | Alpaca_ PIF1 ( ortholog_one2one ) Dog_ PIF1 ( ortholog_one2one ) GuineaPig_ PIF1 ( ortholog_one2one ) Macaque_ PIF1 ( ortholog_one2one ) Mouse_ Pif1 ( ortholog_one2one ) Pig_ PIF1 ( ortholog_one2one ) Rat_ Pif1 ( ortholog_one2one ) Rabbit_ PIF1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Weak ubiquitous expression. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005276(Rat);0.092308(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5FHH (X-ray 3.60A ) 6HPH (X-ray 1.13A ) 6HPQ (X-ray 1.43A ) 6HPT (X-ray 1.44A ) 6HPU (X-ray 3.96A ) |
| DBSNP | rs17802279 |
| Subcellular location [CC] | Nucleus {ECO:0000255|HAMAP-Rule:MF_03176, ECO:0000269|PubMed:16522649, ECO:0000269|PubMed:17172855, ECO:0000269|PubMed:17827721}.; [Isoform 4]: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03176, ECO:0000269|PubMed:23275553}. |
| Mouse PG classification | NA |
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