| Gene Information | |
|---|---|
| Gene Name | PMPCB |
| Organism | Homo sapiens (Human) |
| Gene Length | 489 |
| Protein Names | Mitochondrial-processing peptidase subunit beta (EC 3.4.24.64) (Beta-MPP) (P-52) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000105819 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O75439 |
| Gene Card | PMPCB |
| Uniprot ID | O75439 |
| Pfam | PF00675; PF05193 |
| In ASD | no |
| Allosteric Prediction | yes (0.309217175) |
| Ortholog in Animals | Alpaca_ PMPCB ( ortholog_one2one ) Dog_ PMPCB ( ortholog_one2one ) GuineaPig_ PMPCB ( ortholog_one2one ) Macaque_ PMPCB ( ortholog_one2one ) Mouse_ Pmpcb ( ortholog_one2one ) Pig_ PMPCB ( ortholog_one2one ) Rat_ Pmpcb ( ortholog_one2one ) |
| Ohnologs | UQCRC1 |
| Paralogs | PMPCA, UQCRC1, PITRM1, NRDC, UQCRC2, IDE |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.054124(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs145596167 rs200188353 rs1436866272 rs146343535 rs3087615 rs1461200360 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000269|PubMed:22354088}. |
| Mouse PG classification | NA |
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