| Gene Information | |
|---|---|
| Gene Name | PI3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 117 |
| Protein Names | Elafin (Elastase-specific inhibitor) (ESI) (Peptidase inhibitor 3) (PI-3) (Protease inhibitor WAP3) (Skin-derived antileukoproteinase) (SKALP) (WAP four-disulfide core domain protein 14) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000124102 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P19957 |
| Gene Card | PI3 |
| Uniprot ID | P19957 |
| Pfam | PF10511; PF00095 |
| In ASD | no |
| Allosteric Prediction | no (-0.541994123) |
| Ortholog in Animals | Alpaca_ PI3 ( ortholog_one2one ) Dog_ PI3 ( ortholog_one2one ) Macaque_ PI3 ( ortholog_one2one ) Pig_ SPAI-2 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | WFDC3, WFDC12, WFDC10B, WFDC9, WFDC11, SLPI, WFDC13, WFDC10A, WFDC5 |
| Tissue | esophagus, tonsil, lung, sigmoid.colon, esophagus.mucosa |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1FLE (X-ray 1.90A ) 2REL (NMR - ) 6ATU (X-ray 2.40A ) |
| DBSNP | rs17333103 rs2664581 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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