Gene Information
Gene NamePI15
OrganismHomo sapiens (Human)
Gene Length258
Protein NamesPeptidase inhibitor 15 (PI-15) (25 kDa trypsin inhibitor) (p25TI) (Cysteine-rich secretory protein 8) (CRISP-8) (SugarCrisp)
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000137558 )
Evolutionary StageEumetazoa
AlphaFoldDBO43692
Gene CardPI15
Uniprot IDO43692
PfamPF00188
In ASDno
Allosteric Predictionno (-1.443242576)
Ortholog in AnimalsAlpaca_ PI15 ( ortholog_one2one )
Dog_ PI15 ( ortholog_one2one )
GuineaPig_ PI15 ( ortholog_one2one )
Macaque_ PI15 ( ortholog_one2one )
Mouse_ Pi15 ( ortholog_one2one )
Pig_ PI15 ( ortholog_one2one )
Rat_ Pi15 ( ortholog_one2one )
Rabbit_ PI15 ( ortholog_one2one )
OhnologsR3HDML
ParalogsCRISP2, GLIPR1, CLEC18C, CLEC18A, CLEC18B, R3HDML, CRISPLD1, CRISP1, GLIPR1L1, GLIPR2, GLIPR1L2, CRISPLD2, CRISP3
Tissueappendix, smooth.muscle, oviduct, prostate
Tissue SpecificityWeakly expressed. Expressed at low level in prostate, mammary gland, salivary gland and thyroid gland. {ECO:0000269|PubMed:11287197, ECO:0000269|PubMed:9473672}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Secreted {ECO:0000269|PubMed:8882727}.
Mouse PG classificationNA
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