| Gene Information | |
|---|---|
| Gene Name | FXYD2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 66 |
| Protein Names | Sodium/potassium-transporting ATPase subunit gamma (Na(+)/K(+) ATPase subunit gamma) (FXYD domain-containing ion transport regulator 2) (Sodium pump gamma chain) |
| Target Name | sodium/potassium-transporting atpase subunit gamma |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000137731 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P54710 |
| Gene Card | FXYD2 |
| Uniprot ID | P54710 |
| Pfam | PF02038 |
| In ASD | no |
| Allosteric Prediction | no (-1.000531835) |
| Ortholog in Animals | Alpaca_ FXYD2 ( ortholog_one2one ) Dog_ FXYD2 ( ortholog_one2one ) GuineaPig_ FXYD2 ( ortholog_one2one ) Mouse_ Fxyd2 ( ortholog_one2one ) Rabbit_ FXYD2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FXYD7, FXYD5, FXYD1, FXYD3, FXYD4, FXYD6 |
| Tissue | gall.bladder, kidney, salivary.gland, pancreas, cortex.of.kidney |
| Tissue Specificity | Expressed in the distal convoluted tubule in the kidney. Found on basolateral membranes of nephron epithelial cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2MKV (NMR - ) 7E1Z (EM 3.20A ) 7E20 (EM 2.70A ) 7E21 (EM 2.90A ) |
| DBSNP | rs28938168 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |