| Gene Information | |
|---|---|
| Gene Name | PHT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 577 |
| Protein Names | Solute carrier family 15 member 4 (Peptide transporter 4) (Peptide/histidine transporter 1) (hPHT1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8N697 |
| Gene Card | SLC15A4 |
| Uniprot ID | Q8N697 |
| Pfam | PF00854 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in skeletal muscle. Moderately expressed in kidney, liver, and heart. Weakly expressed in colon and brain. Expressed in low levels throughout the gastrointestinal tract and in Caco-2 cells. Expressed in retinal fragment epithelium (RPE) and neural retina. Expressed in small intestine, stomach, duodenum, jejunum, ileum and colon. {ECO:0000269|PubMed:11741232, ECO:0000269|PubMed:11741260, ECO:0000269|PubMed:16289537}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs33990080 |
| Subcellular location [CC] | Lysosome membrane {ECO:0000269|PubMed:25238095, ECO:0000269|PubMed:29224352, ECO:0000269|PubMed:32433612}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000269|PubMed:32433612}; Multi-pass membrane protein {ECO:0000255}. Early endosome membrane {ECO:0000250|UniProtKB:Q91W98}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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