| Gene Information | |
|---|---|
| Gene Name | UCK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 261 |
| Protein Names | Uridine-cytidine kinase 2 (UCK 2) (EC 2.7.1.48) (Cytidine monophosphokinase 2) (Testis-specific protein TSA903) (Uridine monophosphokinase 2) |
| Target Name | uridine-cytidine kinase 2 |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000143179 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9BZX2 |
| Gene Card | UCK2 |
| Uniprot ID | Q9BZX2 |
| Pfam | PF00485 |
| In ASD | yes |
| Allosteric Prediction | yes (0.050911302) |
| Ortholog in Animals | Alpaca_ UCK2 ( ortholog_one2one ) Dog_ UCK2 ( ortholog_one2one ) GuineaPig_ UCK2 ( ortholog_one2one ) Macaque_ UCK2 ( ortholog_one2one ) Mouse_ Uck2 ( ortholog_one2one ) Pig_ UCK2 ( ortholog_one2one ) Rat_ Uck2 ( ortholog_one2one ) Rabbit_ UCK2 ( ortholog_one2one ) |
| Ohnologs | UCK1 |
| Paralogs | UCK1, UCKL1, UPRT |
| Tissue | NA |
| Tissue Specificity | According to PubMed:8812458; testis-specific. According to PubMed:11306702, placenta-specific. {ECO:0000269|PubMed:8812458}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.094444(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1UDW (X-ray 2.60A ) 1UEI (X-ray 2.60A ) 1UEJ (X-ray 2.61A ) 1UFQ (X-ray 2.50A ) 1UJ2 (X-ray 1.80A ) 1XRJ (X-ray 2.00A ) 6N53 (X-ray 2.70A ) 6N54 (X-ray 2.42A ) 6N55 (X-ray 3.08A ) 6PWZ (X-ray 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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