| Gene Information | |
|---|---|
| Gene Name | PHOX2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 284 |
| Protein Names | Paired mesoderm homeobox protein 2A (ARIX1 homeodomain protein) (Aristaless homeobox protein homolog) (Paired-like homeobox 2A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000165462 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O14813 |
| Gene Card | PHOX2A |
| Uniprot ID | O14813 |
| Pfam | PF00046 |
| In ASD | no |
| Allosteric Prediction | no (-0.925337454) |
| Ortholog in Animals | Alpaca_ PHOX2A ( ortholog_one2one ) Dog_ PHOX2A ( ortholog_one2one ) GuineaPig_ PHOX2A ( ortholog_one2one ) Macaque_ PHOX2A ( ortholog_one2one ) Mouse_ Phox2a ( ortholog_one2one ) Pig_ PHOX2A ( ortholog_one2one ) Rat_ Phox2a ( ortholog_one2one ) Rabbit_ PHOX2A ( ortholog_one2one ) |
| Ohnologs | PHOX2B |
| Paralogs | ARGFX, PAX7, PAX3, ALX4, PAX2, UNCX, RAX2, PAX8, DMBX1, DPRX, PAX5, ISX, ALX3, RHOXF2B, RHOXF2, GSC2, SEBOX, RAX, DRGX, ARX, RHOXF1, PITX3, PRRX1, SHOX, SHOX2, PRRX2, OTX2, PAX4, EVX1, PAX1, PITX2, CRX, PHOX2B, EVX2, ALX1, VSX2, MIXL1, DUXA, PAX6, OTP, HESX1, NOBOX, PROP1, PAX9, GSC, ESX1, DUXB, DUX4, PITX1, OTX1 |
| Tissue | adrenal.gland |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs104894269 rs1041507260 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |
| Mouse PG classification | LPG |
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