| Gene Information | |
|---|---|
| Gene Name | TUSC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 348 |
| Protein Names | Tumor suppressor candidate 3 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3) (Oligosaccharyl transferase subunit TUSC3) (Magnesium uptake/transporter TUSC3) (Protein N33) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000104723 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q13454 |
| Gene Card | TUSC3 |
| Uniprot ID | Q13454 |
| Pfam | PF04756 |
| In ASD | no |
| Allosteric Prediction | no (-0.672487448) |
| Ortholog in Animals | Alpaca_ TUSC3 ( ortholog_one2one ) Dog_ TUSC3 ( ortholog_one2one ) GuineaPig_ TUSC3 ( ortholog_one2one ) Macaque_ TUSC3 ( ortholog_one2one ) Mouse_ Tusc3 ( ortholog_one2one ) Pig_ TUSC3 ( ortholog_one2one ) Rat_ Tusc3 ( ortholog_one2one ) Rabbit_ TUSC3 ( ortholog_one2one ) |
| Ohnologs | MAGT1 |
| Paralogs | MAGT1 |
| Tissue | NA |
| Tissue Specificity | Expressed in most non-lymphoid cells and tissues examined, including prostate, lung, liver, colon, heart, kidney and pancreas. {ECO:0000269|PubMed:12887896}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005276(Rat);0.080000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4M8G (X-ray 2.00A ) 4M90 (X-ray 1.60A ) 4M91 (X-ray 1.10A ) 4M92 (X-ray 1.60A ) |
| DBSNP | rs11545035 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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