Gene Information
Gene NameCEACAM6
OrganismHomo sapiens (Human)
Gene Length344
Protein NamesCarcinoembryonic antigen-related cell adhesion molecule 6 (Non-specific crossreacting antigen) (Normal cross-reacting antigen) (CD antigen CD66c)
Target NameNA
Target TypeNA
Gene Age168 ( ENSG00000086548 )
Evolutionary StageMammalia
AlphaFoldDBP40199
Gene CardCEACAM6
Uniprot IDP40199
PfamPF13895; PF07686
In ASDno
Allosteric Predictionno (-0.702128357)
Ortholog in AnimalsAlpaca_ CEACAM6 ( ortholog_one2one )
Dog_ CEACAM1 ( ortholog_many2many )
Mouse_ Ceacam10 ( ortholog_many2many )
Mouse_ Ceacam1 ( ortholog_many2many )
Mouse_ Ceacam2 ( ortholog_many2many )
Rat_ Ceacam1 ( ortholog_many2many )
Rat_ Ceacam4 ( ortholog_many2many )
Rat_ Ceacam6 ( ortholog_many2many )
OhnologsNA
ParalogsCEACAM19, HEPACAM2, HEPACAM, VSTM5, CEACAM5, CEACAM1, CEACAM3, CEACAM7, CEACAM8, PSG1, PSG8, PSG9, PSG3, PSG7, PSG11, PSG2, PSG4, PSG5, PSG6, CEACAM4, CEACAM21, CEACAM16, CEACAM20, CEACAM18
Tissuelung, esophagus.mucosa, minor.salivary.gland, vagina
Tissue SpecificityExpressed in neutrophils (PubMed:1378450). Expressed in columnar epithelial and goblet cells of the colon (PubMed:10436421). Expressed in numerous tumor cell lines (at protein level) (PubMed:16204051). {ECO:0000269|PubMed:10436421, ECO:0000269|PubMed:1378450, ECO:0000269|PubMed:16204051}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4WHC  (X-ray  2.71A  )  4WTZ  (X-ray  2.52A  )  4Y8A  (X-ray  1.83A  )  4YIQ  (X-ray  1.85A  ) 
DBSNP rs11548735 
Subcellular location [CC]Cell membrane;
Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:2317824}. Apical cell membrane {ECO:0000269|PubMed:10436421}. Cell surface {ECO:0000269|PubMed:1378450, ECO:0000269|PubMed:16204051, ECO:0000269|PubMed:2317824, ECO:0000269|PubMed:8776764, ECO:0000305|PubMed:2803308}. Note=Localized to the apical glycocalyx surface. {ECO:0000269|PubMed:10436421}.
Mouse PG classificationNA
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