| Gene Information | |
|---|---|
| Gene Name | CRPPA |
| Organism | Homo sapiens (Human) |
| Gene Length | 451 |
| Protein Names | D-ribitol-5-phosphate cytidylyltransferase (EC 2.7.7.40) (2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein) (Isoprenoid synthase domain-containing protein) (hISPD) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000214960 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | A4D126 |
| Gene Card | CRPPA |
| Uniprot ID | A4D126 |
| Pfam | PF01128; PF18706 |
| In ASD | no |
| Allosteric Prediction | no (-1.07851337) |
| Ortholog in Animals | Alpaca_ CRPPA ( ortholog_one2one ) Alpaca_ CRPPA ( ortholog_one2many ) Dog_ CRPPA ( ortholog_one2one ) GuineaPig_ CRPPA ( ortholog_one2one ) Macaque_ CRPPA ( ortholog_one2one ) Mouse_ Crppa ( ortholog_one2one ) Pig_ CRPPA ( ortholog_one2one ) Rat_ Crppa ( ortholog_one2one ) Rabbit_ CRPPA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed, with high expression in brain. {ECO:0000269|PubMed:22522420}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4CVH (X-ray 2.39A ) |
| DBSNP | rs587777797 rs397515398 rs387907162 rs752817129 rs369219851 rs397514547 rs566179705 rs397515408 rs387907160 rs1289931198 rs1282788711 rs397515409 rs587777798 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:26687144}. |
| Mouse PG classification | NA |
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