| Gene Information | |
|---|---|
| Gene Name | DVL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 716 |
| Protein Names | Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000161202 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q92997 |
| Gene Card | DVL3 |
| Uniprot ID | Q92997 |
| Pfam | PF00610; PF02377; PF00778; PF12316; PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-0.994284265) |
| Ortholog in Animals | Alpaca_ DVL3 ( ortholog_one2one ) Dog_ DVL3 ( ortholog_one2one ) GuineaPig_ DVL3 ( ortholog_one2one ) Macaque_ DVL3 ( ortholog_one2one ) Mouse_ Dvl3 ( ortholog_one2one ) Pig_ DVL3 ( ortholog_one2one ) Rat_ Dvl3 ( ortholog_one2one ) Rabbit_ DVL3 ( ortholog_one2one ) |
| Ohnologs | DVL2, DVL1 |
| Paralogs | DIXDC1, DVL2, DVL1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6V7O (X-ray 2.90A ) 6ZBQ (X-ray 1.43A ) 6ZBZ (X-ray 1.60A ) 6ZC3 (X-ray 1.67A ) 6ZC4 (X-ray 1.85A ) 6ZC6 (X-ray 1.58A ) 6ZC7 (X-ray 1.48A ) 6ZC8 (X-ray 2.76A ) |
| DBSNP | rs17853048 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:O14641}. |
| Mouse PG classification | NA |
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