| Gene Information | |
|---|---|
| Gene Name | HMCES |
| Organism | Homo sapiens (Human) |
| Gene Length | 354 |
| Protein Names | Abasic site processing protein HMCES (Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein) (ES cell-specific 5hmC-binding protein) (Peptidase HMCES) (EC 3.4.-.-) (SRAP domain-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000183624 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q96FZ2 |
| Gene Card | HMCES |
| Uniprot ID | Q96FZ2 |
| Pfam | PF02586 |
| In ASD | no |
| Allosteric Prediction | no (-1.329995023) |
| Ortholog in Animals | Alpaca_ HMCES ( ortholog_one2one ) Dog_ HMCES ( ortholog_one2one ) Macaque_ HMCES ( ortholog_one2one ) Mouse_ Hmces ( ortholog_one2one ) Pig_ HMCES ( ortholog_one2one ) Rabbit_ HMCES ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5KO9 (X-ray 1.50A ) 6OE7 (X-ray 2.20A ) 6OEA (X-ray 2.10A ) 6OEB (X-ray 2.10A ) 6OOV (X-ray 2.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Chromosome {ECO:0000269|PubMed:30554877}. Note=Recruited to chromatin following DNA damage (PubMed:30554877). Localizes to replication forks (PubMed:30554877). {ECO:0000269|PubMed:30554877}. |
| Mouse PG classification | NA |
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