| Gene Information | |
|---|---|
| Gene Name | STS |
| Organism | Homo sapiens (Human) |
| Gene Length | 583 |
| Protein Names | Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Estrone sulfatase) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase) |
| Target Name | steryl-sulfatase |
| Target Type | Successful target |
| Gene Age | 886 ( ENSG00000101846 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P08842 |
| Gene Card | STS |
| Uniprot ID | P08842 |
| Pfam | PF00884 |
| In ASD | no |
| Allosteric Prediction | yes (0.908764805) |
| Ortholog in Animals | Alpaca_ STS ( ortholog_one2one ) Dog_ STS ( ortholog_one2one ) Macaque_ STS ( ortholog_one2one ) Rat_ Sts ( ortholog_one2one ) |
| Ohnologs | ARSA, GALNS, ARSG |
| Paralogs | IDS, ARSA, ARSL, SULF1, ARSI, ARSG, ARSH, SGSH, GALNS, SULF2, GNS, ARSB, ARSJ, ARSF, ARSD, ARSK |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1P49 (X-ray 2.60A ) |
| DBSNP | rs137853167 rs137853165 rs137853168 rs137853169 rs137853166 rs183370963 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, microneme membrane {ECO:0000269|PubMed:2668275}; Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000269|PubMed:2668275}; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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