Gene Information
Gene NameFAPP2
OrganismHomo sapiens (Human)
Gene Length519
Protein NamesPleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8) (Phosphatidylinositol-four-phosphate adapter protein 2) (FAPP-2) (Phosphoinositol 4-phosphate adapter protein 2) (hFAPP2) (Serologically defined breast cancer antigen NY-BR-86)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ96JA3
Gene CardPLEKHA8
Uniprot IDQ96JA3
PfamPF08718; PF00169
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in kidney cell lines. {ECO:0000269|PubMed:15107860}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5KDI  (X-ray  1.45A 
DBSNP NA 
Subcellular location [CC]Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:15107860}. Membrane;
Peripheral membrane protein {ECO:0000269|PubMed:15107860}. Note=Binds through its PH domain to PtdIns(4)P and ARF1, and subsequently localizes to TGN exit sites. {ECO:0000269|PubMed:15107860}.
Mouse PG classificationNA
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