| Gene Information | |
|---|---|
| Gene Name | TCF7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 384 |
| Protein Names | Transcription factor 7 (TCF-7) (T-cell-specific transcription factor 1) (T-cell factor 1) (TCF-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000081059 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P36402 |
| Gene Card | TCF7 |
| Uniprot ID | P36402 |
| Pfam | PF08347; PF00505 |
| In ASD | no |
| Allosteric Prediction | yes (0.066345444) |
| Ortholog in Animals | Alpaca_ TCF7 ( ortholog_one2one ) GuineaPig_ TCF7 ( ortholog_one2one ) Macaque_ TCF7 ( ortholog_one2one ) Mouse_ Tcf7 ( ortholog_one2one ) Pig_ TCF7 ( ortholog_one2one ) Rat_ Tcf7 ( ortholog_one2one ) Rabbit_ TCF7 ( ortholog_one2one ) |
| Ohnologs | TCF7L2, LEF1, TCF7L1 |
| Paralogs | TCF7L2, TCF7L1, LEF1 |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in T-cells. Also detected in proliferating intestinal epithelial cells and in the basal epithelial cells of mammary gland epithelium. {ECO:0000269|PubMed:10489374}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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