| Gene Information | |
|---|---|
| Gene Name | BMP6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 513 |
| Protein Names | Bone morphogenetic protein 6 (BMP-6) (VG-1-related protein) (VG-1-R) (VGR-1) |
| Target Name | bone morphogenetic protein 6 |
| Target Type | Clinical trial target |
| Gene Age | 645 ( ENSG00000153162 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P22004 |
| Gene Card | BMP6 |
| Uniprot ID | P22004 |
| Pfam | PF00019; PF00688 |
| In ASD | no |
| Allosteric Prediction | yes (0.086300222) |
| Ortholog in Animals | Alpaca_ BMP6 ( ortholog_one2one ) Dog_ BMP6 ( ortholog_one2one ) GuineaPig_ BMP6 ( ortholog_one2one ) Macaque_ BMP6 ( ortholog_one2one ) Mouse_ Bmp6 ( ortholog_one2one ) Pig_ BMP6 ( ortholog_one2one ) Rat_ Bmp6 ( ortholog_one2one ) Rabbit_ BMP6 ( ortholog_one2one ) |
| Ohnologs | BMP7, GDF3, BMP5, BMP8B, BMP8A |
| Paralogs | BMP3, MSTN, INHBC, GDF15, INHBA, GDF6, TGFB3, BMP2, BMP10, TGFB1, INHA, GDF9, GDF11, BMP5, BMP7, INHBB, GDF5, GDF1, GDF2, BMP4, LEFTY1, LEFTY2, GDF3, INHBE, GDF7, GDF10, BMP15, TGFB2, BMP8A, BMP8B, NODAL |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);0.040000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2QCW (X-ray 2.49A ) 2R52 (X-ray 2.50A ) 2R53 (X-ray 2.10A ) 6OMO (X-ray 2.80A ) |
| DBSNP | rs10458105 rs909733732 |
| Subcellular location [CC] | Secreted {ECO:0000250}. |
| Mouse PG classification | NA |
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