Gene Information
Gene NameCEP20
OrganismHomo sapiens (Human)
Gene Length174
Protein NamesCentrosomal protein 20 (FGFR1OP N-terminal-like protein) (FOP-related protein of 20 kDa) (LisH domain-containing protein FOPNL)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000133393 )
3 ( ENSG00000276914 )
Evolutionary StageEukaryota
AlphaFoldDBQ96NB1
Gene CardCEP20
Uniprot IDQ96NB1
PfamPF09398
In ASDno
Allosteric Predictionno (-1.697801309)
Ortholog in AnimalsAlpaca_ CEP20 ( ortholog_one2one )
Dog_ CEP20 ( ortholog_one2one )
GuineaPig_ CEP20 ( ortholog_one2one )
Macaque_ CEP20 ( ortholog_one2one )
Mouse_ Cep20 ( ortholog_one2one )
Pig_ CEP20 ( ortholog_one2one )
Rat_ Cep20 ( ortholog_one2one )
Rabbit_ CEP20 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed. Detected in brain, heart, kidney, liver, lung, skeletal muscle, placenta and intestine. {ECO:0000269|PubMed:20551181}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:26643951}. Cell projection, cilium {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20551181, ECO:0000269|PubMed:24018379}. Cytoplasmic granule {ECO:0000269|PubMed:20551181}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:20551181, ECO:0000269|PubMed:26643951}. Note=Localizes to the centrosome throughout cell cycle progression (PubMed:24018379). Localization to centrioles and pericentriolar satellites may be mediated by KIAA0753/OFIP (PubMed:26643951). {ECO:0000269|PubMed:24018379, ECO:0000269|PubMed:26643951}.
Mouse PG classificationNA
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