| Gene Information | |
|---|---|
| Gene Name | RNF96 |
| Organism | Homo sapiens (Human) |
| Gene Length | 835 |
| Protein Names | Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q13263 |
| Gene Card | TRIM28 |
| Uniprot ID | Q13263 |
| Pfam | PF00628; PF00643; PF14634 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues tested including spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes. {ECO:0000269|PubMed:9016654}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001430(Rat);0.017021(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1FP0 (NMR - ) 2RO1 (NMR - ) 2YVR (X-ray 1.80A ) 6H3A (X-ray 5.50A ) 6I9H (NMR - ) 6QAJ (X-ray 2.90A ) 6QU1 (X-ray 3.70A ) |
| DBSNP | rs56229738 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:10330177, ECO:0000269|PubMed:17178852, ECO:0000269|PubMed:20858735, ECO:0000269|PubMed:23665872, ECO:0000269|PubMed:24741090, ECO:0000269|PubMed:9016654}. Note=Associated with centromeric heterochromatin during cell differentiation through CBX1. {ECO:0000250|UniProtKB:Q62318}. |
| Mouse PG classification | NA |
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