| Gene Information | |
|---|---|
| Gene Name | SLC11A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 550 |
| Protein Names | Natural resistance-associated macrophage protein 1 (NRAMP 1) (Solute carrier family 11 member 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000018280 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P49279 |
| Gene Card | SLC11A1 |
| Uniprot ID | P49279 |
| Pfam | PF01566 |
| In ASD | no |
| Allosteric Prediction | yes (0.224863136) |
| Ortholog in Animals | Alpaca_ SLC11A1 ( ortholog_one2one ) Dog_ SLC11A1 ( ortholog_one2one ) GuineaPig_ SLC11A1 ( ortholog_one2one ) Macaque_ SLC11A1 ( ortholog_one2one ) Mouse_ Slc11a1 ( ortholog_one2one ) Pig_ SLC11A1 ( ortholog_one2one ) Rat_ Slc11a1 ( ortholog_one2one ) Rabbit_ SLC11A1 ( ortholog_one2one ) |
| Ohnologs | SLC11A2 |
| Paralogs | SLC11A2 |
| Tissue | appendix, bone.marrow, lung, spleen, dura.mater, whole.blood |
| Tissue Specificity | Macrophages; peripheral blood leukocytes, lung, spleen and liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs751872662 rs201565523 rs17235409 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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