| Gene Information | |
|---|---|
| Gene Name | PEAK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1746 |
| Protein Names | Inactive tyrosine-protein kinase PEAK1 (Pseudopodium-enriched atypical kinase 1) (Sugen kinase 269) (Tyrosine-protein kinase SgK269) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000173517 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H792 |
| Gene Card | PEAK1 |
| Uniprot ID | Q9H792 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.144554872) |
| Ortholog in Animals | Alpaca_ PEAK1 ( ortholog_one2one ) GuineaPig_ PEAK1 ( ortholog_one2one ) Macaque_ PEAK1 ( ortholog_one2one ) Mouse_ Peak1 ( ortholog_one2one ) Pig_ PEAK1 ( ortholog_one2one ) Rat_ Peak1 ( ortholog_one2one ) Rabbit_ PEAK1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PEAK3, PINK1, PRAG1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6BHC (X-ray 2.30A ) |
| DBSNP | rs35459975 rs56129428 rs35335169 rs34885462 rs56388121 rs12909704 rs56133554 rs56079860 rs1867780 rs34004337 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:20534451, ECO:0000269|PubMed:23105102}. Cell junction, focal adhesion {ECO:0000269|PubMed:20534451, ECO:0000269|PubMed:23105102}. Note=Colocalizes with F-actin in serum-rich medium (PubMed:20534451). Actin colocalization is reduced during serum starvation (PubMed:20534451). {ECO:0000269|PubMed:20534451}. |
| Mouse PG classification | NA |
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