| Gene Information | |
|---|---|
| Gene Name | PGM5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 567 |
| Protein Names | Phosphoglucomutase-like protein 5 (Aciculin) (Phosphoglucomutase-related protein) (PGM-RP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000154330 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q15124 |
| Gene Card | PGM5 |
| Uniprot ID | Q15124 |
| Pfam | PF02878; PF02879; PF02880 |
| In ASD | no |
| Allosteric Prediction | no (-0.283329333) |
| Ortholog in Animals | Alpaca_ PGM5 ( ortholog_one2one ) Alpaca_ PGM5 ( ortholog_one2many ) Dog_ PGM5 ( ortholog_one2one ) GuineaPig_ PGM5 ( ortholog_one2one ) Macaque_ PGM5 ( ortholog_one2one ) Mouse_ Pgm5 ( ortholog_one2one ) Pig_ PGM5 ( ortholog_one2one ) Rat_ Pgm5 ( ortholog_one2one ) Rabbit_ PGM5 ( ortholog_one2one ) |
| Ohnologs | PGM1 |
| Paralogs | PGM1, PGM2L1, PGM2, PGM3, PRTFDC1, HPRT1 |
| Tissue | NA |
| Tissue Specificity | Detected in smooth and cardiac muscle at high levels and in skeletal muscle at low level. Present in other tissues due to vascular or other smooth muscle component. Low levels are present in liver, kidney, skin and brain (at protein level). {ECO:0000269|PubMed:8175905, ECO:0000269|PubMed:8631316}. |
| Pharmacological Animal Models | 0.037222(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell junction, adherens junction {ECO:0000269|PubMed:8175905}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:8175905}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q8BZF8}. Note=Concentrated in focal contacts at the ends of actin bundles, and associated with actin filaments. {ECO:0000269|PubMed:8175905}. |
| Mouse PG classification | NA |
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