| Gene Information | |
|---|---|
| Gene Name | IL12A |
| Organism | Homo sapiens (Human) |
| Gene Length | 219 |
| Protein Names | Interleukin-12 subunit alpha (IL-12A) (Cytotoxic lymphocyte maturation factor 35 kDa subunit) (CLMF p35) (IL-12 subunit p35) (NK cell stimulatory factor chain 1) (NKSF1) |
| Target Name | interleukin-12 alpha |
| Target Type | Successful target |
| Gene Age | 645 ( ENSG00000168811 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P29459 |
| Gene Card | IL12A |
| Uniprot ID | P29459 |
| Pfam | PF03039 |
| In ASD | no |
| Allosteric Prediction | no (-0.31657098) |
| Ortholog in Animals | Alpaca_ IL12A ( ortholog_one2one ) Dog_ IL12A ( ortholog_one2one ) GuineaPig_ Il12a ( ortholog_one2one ) Macaque_ IL12A ( ortholog_one2one ) Mouse_ Il12a ( ortholog_one2one ) Pig_ IL12A ( ortholog_one2one ) Rat_ Il12a ( ortholog_one2one ) Rabbit_ IL12A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1F45 (X-ray 2.80A ) 3HMX (X-ray 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:1674604, ECO:0000269|PubMed:9342359}. |
| Mouse PG classification | NA |
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