| Gene Information | |
|---|---|
| Gene Name | PGLYRP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 196 |
| Protein Names | Peptidoglycan recognition protein 1 (Peptidoglycan recognition protein short) (PGRP-S) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000008438 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O75594 |
| Gene Card | PGLYRP1 |
| Uniprot ID | O75594 |
| Pfam | PF01510 |
| In ASD | no |
| Allosteric Prediction | no (-0.152424769) |
| Ortholog in Animals | Alpaca_ PGLYRP1 ( ortholog_one2one ) Dog_ PGLYRP1 ( ortholog_one2one ) GuineaPig_ PGLYRP1 ( ortholog_one2one ) Macaque_ PGLYRP1 ( ortholog_one2one ) Mouse_ Pglyrp1 ( ortholog_one2one ) Pig_ PGLYRP1 ( ortholog_one2one ) Rat_ Pglyrp1 ( ortholog_one2one ) Rabbit_ PGLYRP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PGLYRP3, PGLYRP4, PGLYRP2 |
| Tissue | bone.marrow, spleen, whole.blood |
| Tissue Specificity | Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils. {ECO:0000269|PubMed:11461926, ECO:0000269|PubMed:9707603}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1YCK (X-ray 1.70A ) |
| DBSNP | rs34180629 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:16354652}. Cytoplasmic granule {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |