| Gene Information | |
|---|---|
| Gene Name | SMU1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 513 |
| Protein Names | WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000122692 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q2TAY7 |
| Gene Card | SMU1 |
| Uniprot ID | Q2TAY7 |
| Pfam | PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-0.470298595) |
| Ortholog in Animals | Alpaca_ SMU1 ( ortholog_one2one ) Dog_ SMU1 ( ortholog_one2one ) GuineaPig_ SMU1 ( ortholog_one2one ) Macaque_ SMU1 ( ortholog_one2one ) Mouse_ Smu1 ( ortholog_one2one ) Pig_ SMU1 ( ortholog_one2one ) Rat_ Smu1 ( ortholog_one2one ) Rabbit_ SMU1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.327618(Chimpanzee);0.088188(Mouse);0.001899(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5O9Z (EM 4.50A ) 6AHD (EM 3.80A ) 6Q8F (X-ray 1.90A ) 6Q8I (X-ray 3.17A ) 6Q8J (X-ray 1.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q99M63}. Nucleus {ECO:0000269|PubMed:24945353, ECO:0000269|PubMed:28781166}. Nucleus speckle {ECO:0000250|UniProtKB:Q76B40}. Note=Colocalizes with SRSF1 in nuclear speckles. {ECO:0000250|UniProtKB:Q76B40}. |
| Mouse PG classification | NA |
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