| Gene Information | |
|---|---|
| Gene Name | SLC14A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 920 |
| Protein Names | Urea transporter 2 (Solute carrier family 14 member 2) (Urea transporter, kidney) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000132874 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15849 |
| Gene Card | SLC14A2 |
| Uniprot ID | Q15849 |
| Pfam | PF03253 |
| In ASD | no |
| Allosteric Prediction | no (-0.346159222) |
| Ortholog in Animals | Alpaca_ SLC14A2 ( ortholog_one2one ) GuineaPig_ SLC14A2 ( ortholog_one2one ) Macaque_ SLC14A2 ( ortholog_one2one ) Mouse_ Slc14a2 ( ortholog_one2one ) Pig_ SLC14A2 ( ortholog_one2one ) Rat_ Slc14a2 ( ortholog_one2one ) Rabbit_ SLC14A2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC14A1 |
| Tissue | appendix |
| Tissue Specificity | [Isoform 1]: Epressed in the inner medulla of the kidney (at protein level). {ECO:0000269|PubMed:11502588}.; [Isoform 2]: Expressed in the kidney. {ECO:0000269|PubMed:8647271}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34461862 rs1484873 rs35245152 rs9960464 rs1123617 rs3745009 |
| Subcellular location [CC] | [Isoform 1]: Apical cell membrane {ECO:0000269|PubMed:17702749}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:17702749}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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