| Gene Information | |
|---|---|
| Gene Name | PGLYRP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 576 |
| Protein Names | N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) (Peptidoglycan recognition protein 2) (Peptidoglycan recognition protein long) (PGRP-L) |
| Target Name | n-acetylmuramoyl-l-alanine amidase |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000161031 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q96PD5 |
| Gene Card | PGLYRP2 |
| Uniprot ID | Q96PD5 |
| Pfam | PF01510 |
| In ASD | no |
| Allosteric Prediction | no (-0.652975573) |
| Ortholog in Animals | Alpaca_ PGLYRP2 ( ortholog_one2one ) Dog_ PGLYRP2 ( ortholog_one2one ) GuineaPig_ PGLYRP2 ( ortholog_one2one ) Macaque_ PGLYRP2 ( ortholog_one2one ) Mouse_ Pglyrp2 ( ortholog_one2one ) Pig_ PGLYRP2 ( ortholog_one2one ) Rat_ Pglyrp2 ( ortholog_one2one ) Rabbit_ PGLYRP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PGLYRP1, PGLYRP3, PGLYRP4 |
| Tissue | liver |
| Tissue Specificity | Strongly expressed in liver and fetal liver, and secreted into serum. Expressed to a much lesser extent in transverse colon, lymph nodes, heart, thymus, pancreas, descending colon, stomach and testis. Isoform 2 is not detected in the liver or serum. {ECO:0000269|PubMed:11461926, ECO:0000269|PubMed:16054449}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs3813135 rs733731 rs28404490 rs892145 rs34440547 rs2304200 |
| Subcellular location [CC] | Secreted. Membrane. |
| Mouse PG classification | NA |
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