| Gene Information | |
|---|---|
| Gene Name | PGC |
| Organism | Homo sapiens (Human) |
| Gene Length | 388 |
| Protein Names | Gastricsin (EC 3.4.23.3) (Pepsinogen C) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000096088 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P20142 |
| Gene Card | PGC |
| Uniprot ID | P20142 |
| Pfam | PF07966; PF00026 |
| In ASD | no |
| Allosteric Prediction | yes (0.039191188) |
| Ortholog in Animals | Alpaca_ PGC ( ortholog_one2one ) Alpaca_ PGC ( ortholog_one2many ) GuineaPig_ Pgc ( ortholog_one2one ) Macaque_ PGC ( ortholog_one2one ) Mouse_ Pgc ( ortholog_one2one ) Pig_ PGC ( ortholog_one2one ) Rat_ Pgc ( ortholog_one2one ) |
| Ohnologs | REN, CTSE |
| Paralogs | BACE2, REN, CTSE, BACE1, NAPSA, CTSD, PGA5, PGA4, PGA3 |
| Tissue | stomach, pancreas, lung |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1AVF (X-ray 2.36A ) 1HTR (X-ray 1.62A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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