| Gene Information | |
|---|---|
| Gene Name | PGAP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 320 |
| Protein Names | Post-GPI attachment to proteins factor 3 (COS16 homolog) (hCOS16) (Gene coamplified with ERBB2 protein) (PER1-like domain-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000161395 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96FM1 |
| Gene Card | PGAP3 |
| Uniprot ID | Q96FM1 |
| Pfam | PF04080 |
| In ASD | no |
| Allosteric Prediction | no (-1.292895309) |
| Ortholog in Animals | Alpaca_ PGAP3 ( ortholog_one2one ) Dog_ PGAP3 ( ortholog_one2one ) GuineaPig_ PGAP3 ( ortholog_one2one ) Macaque_ PGAP3 ( ortholog_one2one ) Mouse_ Pgap3 ( ortholog_one2one ) Pig_ PGAP3 ( ortholog_one2one ) Rat_ Pgap3 ( ortholog_one2one ) Rabbit_ PGAP3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed, with highest levels in thyroid and placenta. {ECO:0000269|PubMed:12460457}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.175650(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs587777251 rs371549948 rs759541820 rs587777252 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000305|PubMed:12460457}; Multi-pass membrane protein {ECO:0000305|PubMed:12460457}. Endoplasmic reticulum membrane {ECO:0000305|PubMed:12460457}; Multi-pass membrane protein {ECO:0000305|PubMed:12460457}. Note=Mainly localizes to Golgi apparatus. {ECO:0000305}. |
| Mouse PG classification | LPG |
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