| Gene Information | |
|---|---|
| Gene Name | CPSF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1443 |
| Protein Names | Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000071894 ) 3 ( ENSG00000285049 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q10570 |
| Gene Card | CPSF1 |
| Uniprot ID | Q10570 |
| Pfam | PF03178; PF10433 |
| In ASD | no |
| Allosteric Prediction | no (-0.572786321) |
| Ortholog in Animals | Dog_ CPSF1 ( ortholog_one2one ) GuineaPig_ CPSF1 ( ortholog_one2one ) Mouse_ Cpsf1 ( ortholog_one2one ) Rat_ Cpsf1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DDB1, SF3B3 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with high expression in the retina. {ECO:0000269|PubMed:30689892}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6BLY (EM 3.36A ) 6BM0 (EM 3.80A ) 6DNH (EM 3.40A ) 6F9N (X-ray 2.50A ) 6FBS 6FUW (EM 3.07A ) 6URG (EM 3.00A ) 6URO (EM 3.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus, nucleoplasm. |
| Mouse PG classification | NA |
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