| Gene Information | |
|---|---|
| Gene Name | PFKFB4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 469 |
| Protein Names | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (6PF-2-K/Fru-2,6-P2ase 4) (PFK/FBPase 4) (6PF-2-K/Fru-2,6-P2ase testis-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)] |
| Target Name | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000114268 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q16877 |
| Gene Card | PFKFB4 |
| Uniprot ID | Q16877 |
| Pfam | PF01591; PF00300 |
| In ASD | yes |
| Allosteric Prediction | yes (0.999594176) |
| Ortholog in Animals | Alpaca_ PFKFB4 ( ortholog_one2one ) Dog_ PFKFB4 ( ortholog_one2one ) GuineaPig_ PFKFB4 ( ortholog_one2one ) Macaque_ PFKFB4 ( ortholog_one2one ) Mouse_ Pfkfb4 ( ortholog_one2one ) Pig_ PFKFB4 ( ortholog_one2one ) Rat_ Pfkfb4 ( ortholog_one2one ) Rabbit_ PFKFB4 ( ortholog_one2one ) |
| Ohnologs | PFKFB1, PFKFB3, PFKFB2 |
| Paralogs | PFKFB1, PFKFB2, PFKFB3 |
| Tissue | duodenum, placenta, small.intestine, testis, whole.blood |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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