| Gene Information | |
|---|---|
| Gene Name | PFKFB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 505 |
| Protein Names | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (6PF-2-K/Fru-2,6-P2ase 2) (PFK/FBPase 2) (6PF-2-K/Fru-2,6-P2ase heart-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000123836 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O60825 |
| Gene Card | PFKFB2 |
| Uniprot ID | O60825 |
| Pfam | PF01591; PF00300 |
| In ASD | no |
| Allosteric Prediction | yes (1.106464878) |
| Ortholog in Animals | Alpaca_ PFKFB2 ( ortholog_one2one ) Dog_ PFKFB2 ( ortholog_one2one ) GuineaPig_ PFKFB2 ( ortholog_one2one ) Macaque_ PFKFB2 ( ortholog_one2one ) Mouse_ Pfkfb2 ( ortholog_one2one ) Pig_ PFKFB2 ( ortholog_one2one ) Rat_ Pfkfb2 ( ortholog_one2one ) Rabbit_ PFKFB2 ( ortholog_one2one ) |
| Ohnologs | PFKFB4, PFKFB1, PFKFB3 |
| Paralogs | PFKFB3, PFKFB4, PFKFB1 |
| Tissue | NA |
| Tissue Specificity | Heart. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.023529(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5HTK (X-ray 2.01A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
| click here to return to the previous page | |