| Gene Information | |
|---|---|
| Gene Name | PSMG1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 288 |
| Protein Names | Proteasome assembly chaperone 1 (PAC-1) (Chromosome 21 leucine-rich protein) (C21-LRP) (Down syndrome critical region protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000183527 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95456 |
| Gene Card | PSMG1 |
| Uniprot ID | O95456 |
| Pfam | PF16094 |
| In ASD | no |
| Allosteric Prediction | no (-1.239728862) |
| Ortholog in Animals | Alpaca_ PSMG1 ( ortholog_one2one ) GuineaPig_ PSMG1 ( ortholog_one2one ) Macaque_ PSMG1 ( ortholog_one2one ) Mouse_ Psmg1 ( ortholog_one2one ) Pig_ PSMG1 ( ortholog_one2one ) Rat_ Psmg1 ( ortholog_one2one ) Rabbit_ PSMG1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | In the adult, detected in brain, colon, leukocytes, breast and testis. Widely expressed in the fetus. Also expressed in a variety of proliferating cell lines. {ECO:0000269|PubMed:10872820, ECO:0000269|PubMed:9784380}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);0.009524(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs8131611 |
| Subcellular location [CC] | Cytoplasm. Endoplasmic reticulum. |
| Mouse PG classification | NA |
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