| Gene Information | |
|---|---|
| Gene Name | PFAS |
| Organism | Homo sapiens (Human) |
| Gene Length | 1338 |
| Protein Names | Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase) (Phosphoribosylformylglycineamide amidotransferase) |
| Target Name | phosphoribosylformylglycinamidine synthase |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000178921 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O15067 |
| Gene Card | PFAS |
| Uniprot ID | O15067 |
| Pfam | PF02769; PF18072; PF18076 |
| In ASD | no |
| Allosteric Prediction | yes (0.673958023) |
| Ortholog in Animals | Alpaca_ PFAS ( ortholog_one2one ) Dog_ PFAS ( ortholog_one2one ) GuineaPig_ PFAS ( ortholog_one2one ) Macaque_ PFAS ( ortholog_one2one ) Mouse_ Pfas ( ortholog_one2one ) Rat_ Pfas ( ortholog_one2one ) Rabbit_ PFAS ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001516(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9891699 rs4791641 rs35217368 rs11078738 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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