| Gene Information | |
|---|---|
| Gene Name | SBDS |
| Organism | Homo sapiens (Human) |
| Gene Length | 250 |
| Protein Names | Ribosome maturation protein SBDS (Shwachman-Bodian-Diamond syndrome protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000126524 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q9Y3A5 |
| Gene Card | SBDS |
| Uniprot ID | Q9Y3A5 |
| Pfam | PF01172; PF20268; PF09377 |
| In ASD | no |
| Allosteric Prediction | no (-0.956102726) |
| Ortholog in Animals | Alpaca_ SBDS ( ortholog_one2one ) GuineaPig_ SBDS ( ortholog_one2one ) Macaque_ SBDS ( ortholog_one2many ) Mouse_ Sbds ( ortholog_one2one ) Pig_ SBDS ( ortholog_one2one ) Rat_ Sbds ( ortholog_one2one ) Rabbit_ SBDS ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KDO (NMR - ) 2L9N (NMR - ) 5AN9 (EM 3.30A ) 5ANB (EM 4.10A ) 5ANC (EM 4.20A ) 6QKL (EM 3.30A ) |
| DBSNP | rs28942099 rs373730800 rs1554341516 rs1554341499 rs1554341363 rs113993995 rs113993996 rs79344818 |
| Subcellular location [CC] | Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Note=Primarily detected in the cytoplasm, and at low levels in nucleus and nucleolus (PubMed:19602484 and PubMed:17475909). Detected in the nucleolus during G1 and G2 phase of the cell cycle, and diffusely distributed in the nucleus during S phase. Detected at the mitotic spindle. Colocalizes with the microtubule organizing center during interphase (PubMed:19759903). {ECO:0000269|PubMed:19759903}. |
| Mouse PG classification | LPG |
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