| Gene Information | |
|---|---|
| Gene Name | PEZ |
| Organism | Homo sapiens (Human) |
| Gene Length | 1187 |
| Protein Names | Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q15678 |
| Gene Card | PTPN14 |
| Uniprot ID | Q15678 |
| Pfam | PF09380; PF00373; PF09379; PF00102 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2BZL (X-ray 1.65A ) 6IWD (X-ray 1.80A ) 6JJW (X-ray 2.40A ) |
| DBSNP | rs112523432 rs12239356 |
| Subcellular location [CC] | Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus. Note=Translocation into the nucleus is associated with induction of cell proliferation. Partially colocalized with actin filaments at the plasma membrane. |
| Mouse PG classification | NA |
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