| Gene Information | |
|---|---|
| Gene Name | PEX19 |
| Organism | Homo sapiens (Human) |
| Gene Length | 299 |
| Protein Names | Peroxisomal biogenesis factor 19 (33 kDa housekeeping protein) (Peroxin-19) (Peroxisomal farnesylated protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000162735 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P40855 |
| Gene Card | ENSG00000258465;PEX19 |
| Uniprot ID | P40855 |
| Pfam | PF04614 |
| In ASD | no |
| Allosteric Prediction | no (-0.950464419) |
| Ortholog in Animals | Alpaca_ PEX19 ( ortholog_one2one ) Dog_ PEX19 ( ortholog_one2one ) GuineaPig_ PEX19 ( ortholog_one2one ) Mouse_ Pex19 ( ortholog_one2one ) Pig_ PEX19 ( ortholog_one2one ) Rat_ Pex19 ( ortholog_one2many ) Rabbit_ PEX19 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Isoform 1 is strongly predominant in all tissues except in utero where isoform 2 is the main form. {ECO:0000269|PubMed:9339377}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.076055(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2W85 (NMR - ) 2WL8 (X-ray 2.05A ) 3AJB (X-ray 2.50A ) 3MK4 (X-ray 2.42A ) 5LNF (NMR - ) |
| DBSNP | rs11550119 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10704444, ECO:0000269|PubMed:11259404, ECO:0000269|PubMed:15007061}. Peroxisome membrane {ECO:0000269|PubMed:10051604, ECO:0000269|PubMed:10704444, ECO:0000269|PubMed:15007061, ECO:0000269|PubMed:9339377}; Lipid-anchor {ECO:0000269|PubMed:10051604, ECO:0000269|PubMed:9339377}; Cytoplasmic side {ECO:0000269|PubMed:10051604, ECO:0000269|PubMed:9339377}. Note=Mainly cytoplasmic. Some fraction membrane-associated to the outer surface of peroxisomes. {ECO:0000269|PubMed:10704444, ECO:0000269|PubMed:15007061}. |
| Mouse PG classification | NA |
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