| Gene Information | |
|---|---|
| Gene Name | PESCRG3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 280 |
| Protein Names | Borealin (Cell division cycle-associated protein 8) (Dasra-B) (hDasra-B) (Pluripotent embryonic stem cell-related gene 3 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q53HL2 |
| Gene Card | CDCA8 |
| Uniprot ID | Q53HL2 |
| Pfam | PF10512; PF10444 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001759(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KDD (NMR - ) 2QFA (X-ray 1.40A ) 2RAW (X-ray 2.40A ) 2RAX (X-ray 3.30A ) 6YIE (X-ray 3.49A ) 6YIF (X-ray 1.81A ) 6YIH (X-ray 2.55A ) |
| DBSNP | rs17851453 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:18946085}. Cytoplasm {ECO:0000269|PubMed:18946085}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:15561729}. Chromosome, centromere {ECO:0000269|PubMed:20739936}. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with SENP3 in the nucleolus in interphase cells. {ECO:0000269|PubMed:18946085}. |
| Mouse PG classification | NA |
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