| Gene Information | |
|---|---|
| Gene Name | PELI3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 469 |
| Protein Names | E3 ubiquitin-protein ligase pellino homolog 3 (Pellino-3) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase pellino homolog 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000174516 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N2H9 |
| Gene Card | PELI3 |
| Uniprot ID | Q8N2H9 |
| Pfam | PF04710 |
| In ASD | no |
| Allosteric Prediction | no (-0.649258187) |
| Ortholog in Animals | Alpaca_ PELI3 ( ortholog_one2one ) Dog_ PELI3 ( ortholog_one2one ) GuineaPig_ PELI3 ( ortholog_one2one ) Macaque_ PELI3 ( ortholog_one2one ) Mouse_ Peli3 ( ortholog_one2one ) Pig_ PELI3 ( ortholog_one2one ) Rat_ Peli3 ( ortholog_one2one ) Rabbit_ PELI3 ( ortholog_one2one ) |
| Ohnologs | PELI2, PELI1 |
| Paralogs | PELI1, PELI2 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain, heart and testis, and at lower level in kidney, liver, lung, placenta, small intestine, spleen and stomach. Isoform 1 is not expressed in lung. {ECO:0000269|PubMed:12874243}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34989499 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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