| Gene Information | |
|---|---|
| Gene Name | PEDF |
| Organism | Homo sapiens (Human) |
| Gene Length | 418 |
| Protein Names | Pigment epithelium-derived factor (PEDF) (Cell proliferation-inducing gene 35 protein) (EPC-1) (Serpin F1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P36955 |
| Gene Card | SERPINF1 |
| Uniprot ID | P36955 |
| Pfam | PF00079 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Retinal pigment epithelial cells and blood plasma. {ECO:0000269|PubMed:12737624}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1IMV (X-ray 2.85A ) |
| DBSNP | rs1136287 rs1804145 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Enriched in stage I melanosomes. |
| Mouse PG classification | NA |
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